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精萘毒理學資料及環(huán)境行為

來源:http://mc-downloads.com/ 日期:2024-04-22 發(fā)布人:創(chuàng)始人

毒性:屬低毒類。

Toxicity: Belongs to the low toxicity category.

急性毒性:LD50490mg/kg(大鼠經(jīng)口);人經(jīng)口5g,白內(nèi)障及腎損害;人經(jīng)口5~15g,致死;兒童經(jīng)口2.0g/2日,致死。

Acute toxicity: LD50490mg/kg (orally administered to rats); Oral administration of 5g, cataracts and kidney damage; 5-15g per person via oral route, fatal; Children die from oral ingestion of 2.0g/2 per day.

亞急性和慢性毒性:兔經(jīng)口1g/(kg·天),3天,見晶狀體渾濁,20天后形成白內(nèi)障。兔吸入飽和蒸氣2小時/天,2~3個月,紅細胞先增多后減少;400~500mg/m3,4小時/天,5個月,見晶狀體渾濁。小鼠吸入60~500mg/m3,5個月,條件反射紊亂,尸檢見呼吸系統(tǒng)損害。

Subacute and chronic toxicity: 1g/(kg · day) orally administered to rabbits for 3 days, with lens opacity observed and cataracts formed 20 days later. Rabbits inhale saturated vapor for 2 hours/day, 2-3 months, and red blood cells first increase and then decrease; 400-500mg/m3, 4 hours/day, 5 months, with lens opacity observed. Mice inhaled 60-500mg/m3 for 5 months, with disrupted conditioned reflexes and respiratory system damage observed at autopsy.

致突變性:細胞遺傳學分析:倉鼠卵巢30mg/L。姊妹染色單體交換:倉鼠卵巢15mg/L。

Mutagenicity: Cytogenetic analysis: Hamster ovary 30mg/L. Sister chromatid exchange: Hamster ovary 15mg/L.

生殖毒性:小鼠經(jīng)口最低中毒劑量(TDL0):2400mg/kg(孕7~14天),影響活產(chǎn)指數(shù),影響存活指數(shù)(如活產(chǎn)在第4天時的存活數(shù))。

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Reproductive toxicity: The lowest oral toxic dose (TDL0) in mice is 2400mg/kg (7-14 days of pregnancy), which affects the live birth index and the survival index (such as the number of live births on the 4th day).

致癌性:大鼠皮下最低中毒劑量(TDL0):3500mg/kg(12周,間歇),疑致腫瘤劑,致淋巴瘤,包括何杰金氏病,致子宮腫瘤。小鼠吸入最低中毒濃度(TCL0):30ppm(6小時)(2處,間歇),致腫瘤,致肺腫瘤。

Carcinogenicity: Subcutaneous minimum toxic dose (TDL0) in rats: 3500mg/kg (12 weeks, intermittent), suspected to be a tumor causing agent, causing lymphoma, including Hodgkin's disease, and causing uterine tumors. Mouse inhalation of the lowest toxic concentration (TCL0): 30ppm (6 hours) (2 places, intermittent), causing tumors and lung tumors.

在環(huán)境中的遷移幾個實驗證明了多環(huán)芳烴(PAHs)的可生物降解性。低分子量的多環(huán)芳香烴(PAHs)如萘、苊、苊烯在實驗研究中均能快速地被降解。初始濃度為5~10mg/L的液體,在7天之內(nèi)有90%以上的多環(huán)芳香(PAHs)被生物降解。高分子量的多環(huán)芳香烴(PAHs)如熒蒽、苯并(a)蒽、屈、苯并(a)芘和和蒽等很難被 生物降解。

Several experiments on migration in the environment have demonstrated the biodegradability of polycyclic aromatic hydrocarbons (PAHs). Low molecular weight polycyclic aromatic hydrocarbons (PAHs) such as naphthalene, acenaphthene, and acenaphthene can be rapidly degraded in experimental studies. A liquid with an initial concentration of 5-10mg/L can biodegrade over 90% of polycyclic aromatic hydrocarbons (PAHs) within 7 days. High molecular weight polycyclic aromatic hydrocarbons (PAHs) such as fluoranthene, benzo (a) anthracene, quinone, benzo (a) pyrene, and anthracene are difficult to biodegrade.

危險特性:遇明火、高熱可燃。燃燒時放出有毒的刺激性煙霧。與強氧化劑如鉻酸酐、氯酸鹽和高錳酸鉀等接觸,能發(fā)生強烈反應(yīng),引起燃燒或爆炸。粉體與空氣可形成爆炸性混合物,當達到一定的濃度時,遇火星會發(fā)生爆炸。

Hazardous characteristics: flammable in the presence of open flames and high heat. Toxic and irritating smoke is emitted during combustion. When in contact with strong oxidants such as chromic anhydride, chlorate, and potassium permanganate, a strong reaction can occur, causing combustion or explosion. Powder and air can form explosive mixtures, and when they reach a certain concentration, they will explode when encountering Mars.

燃燒(分解)產(chǎn)物:一氧化碳、二氧化碳。

Combustion (decomposition) products: carbon monoxide, carbon dioxide.

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